Syncing two carbs is easier than syncing four.
Changing the cam chain and roller on a Honda is a PITA.
An OIF Bonnie weighs 50+ pounds less than your Thruxton.
Buying used parts on the interwebs is great. But sometimes you have to walk into a knowledgeable shop, lay your part on the counter and get some advice. Bob Raber is 1,000 cooler and more knowledgeable than a-certain-someone at the popular used Honda joint.
I could buy brand new repop fork tubes for my Bonnie. I could not find new repop fork tubes for my CB350.
Not that I'm a good mechanic by any stretch of the imagination, but I could help you with an OIF bike. I don't know much about Hondasakis. However, James does.
I am, by no means, down on old Hondas et. al. They are cool-ass bikes. However, I've found the '70s Brit twins to be very straightforward and easy to work on. And parts are plentiful.
This 450 was hot shit (till it broke down a mile from this picture). I'd do my CB350 like this if I were keeping it:

Let Dave, Ryan, and James comment here. They all have/had CBs.